MCS-200

The MCS-200 from Bio-Logic is a compact stopped-flow spectrophotometer optimized for rapid kinetics measurements in biochemistry and biophysics, combining efficient mixing with sensitive optical detection in a space-efficient design.

Mixing and dead time:
– Stopped-flow mixing: two syringes, pneumatic drive
– Dead time: <2 ms (1 ms with optimized flow cell) - Observation cell: 2 mm or 10 mm path length options - Sample volume per shot: ~150 µL - Minimum sample volume: 0.5 mL per syringe Detection modes: - UV/Vis absorbance: single wavelength with PMT - Fluorescence: right-angle detection with PMT - Wavelength: 250-700 nm - Time resolution: 100 µs after dead time Temperature control: - Syringe and cell block: -10 to +70°C (Peltier) - Stability: +/-0.1°C - Pre-equilibration of both syringes before mixing Applications: - Enzyme kinetics: substrate binding and catalysis - Protein-ligand binding: association/dissociation rates - Protein folding: refolding after denaturant dilution - Metal ion binding: coordination chemistry kinetics - Antibody-antigen association: immunological kinetics Data acquisition: - Time range: 0.5 ms to 1000 s per acquisition - Averaging: multiple shots for improved S/N - Software: kinetics fitting with single and multi-exponential models NewRoad provides Bio-Logic MCS-200 in Israel for biochemistry and biophysics rapid kinetics research.