µSFM

The µSFM (micro stopped-flow) from Bio-Logic is a miniaturized stopped-flow system designed for rapid kinetics experiments where sample availability is limited, offering the same mixing performance and MOS module compatibility as the full-scale SFM series but with dramatically reduced sample consumption.

Micro-scale mixing:
– Dead time: <2 ms (same as full-scale SFM) - Sample volume per shot: 8 µL (vs 80-200 µL in standard SFM) - Observation cell volume: 1.5 µL - Minimum sample per experiment: 0.1 mL per syringe - 10-fold reduction in sample consumption vs SFM-2000 Compatibility: - Same MOS module interface as SFM-2000, SFM-3000, SFM-4000 - Compatible with MOS-200, MOS-500, MOS-DAD - Detection: UV/Vis absorbance, fluorescence, CD, diode array - BioKine32 software for data acquisition and fitting Design: - Miniaturized mixing block and observation cell - Pneumatic drive: same speed and reproducibility as full SFM - Temperature control: -10 to +70°C Peltier - Cell path lengths: 1.5 mm (standard) or 10 mm (high sensitivity) Ideal applications: - Recombinant proteins: limited expression yield - Isotopically labelled proteins: expensive preparation - Rare enzymes or substrates: natural product studies - Single-molecule labelled samples: FRET pairs - High-throughput screening: test many conditions on small batches NewRoad provides Bio-Logic µSFM in Israel for research groups with scarce or expensive samples requiring rapid kinetics.